Scientists have found new evidence suggesting that RNA, a molecule essential for life, may have formed naturally under early Earth conditions. The study, published on December 15 in the journal Proceedings of the National Academy of Sciences, challenges long-standing assumptions about how difficult the origin of life’s building blocks might have been.
RNA plays a central role in living systems by helping convert genetic information into proteins. Many scientists believe RNA existed before DNA, forming the basis of the RNA world hypothesis, which proposes that early life relied solely on RNA. However, explaining how RNA formed without biological processes has remained a major challenge.
The research team recreated chemical environments believed to exist more than four billion years ago. They combined ribose sugars, phosphates, nucleobases, borates and basalt rock, then subjected the mixture to repeated heating and drying cycles. These conditions are thought to resemble ancient underground aquifers on early Earth.
Contrary to earlier beliefs, borates did not block RNA formation. Instead, they helped stabilise ribose and supported key chemical reactions needed to assemble RNA. The findings suggest RNA could have formed more easily than previously thought, reshaping theories about the origins of life on Earth and possibly beyond.
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